SINGLE-CELL RNA SEQUENCING UNVEILS THE ACTIVATION OF EGR1-ATF3 SIGNALING IN EGR1 + MUSCLE STEM CELLS DURING HUMAN PARAVERTEBRAL MUSCLE DEGENERATION

Single-cell RNA sequencing unveils the activation of EGR1-ATF3 signaling in EGR1 + muscle stem cells during human paravertebral muscle degeneration

Background: Paravertebral muscles (PVM) degeneration (PMD) is closely associated with low back pain.Muscle stem cells (MuSCs) can promote muscle regeneration and repair.However, our understanding of the cellular composition of PVM and the key genes-mediated MuSCs functions is limited.Methods: We analyzed cells heterogeneity and identified key genes

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Different types of drug abusers prefrontal cortex activation patterns and based on machine-learning classification

Drug addiction can cause abnormal brain activation changes, which are the root cause of drug craving and brain function errors.This study enrolled drug abusers to determine the effects of different drugs on brain activation.A functional near-infrared spectroscopy (fNIRS) device was used for the research.This study was designed with an experimental

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Analysis of the correlation between thyroid hormones and thyroid volume by gender: A volumetric computed tomography study

The aim of this study was to evaluate the correlation between triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone (TSH) hormones and thyroid gland volume with volumetric analysis performed by using computed tomography (CT) images.In this retrospective study, IV contrasted thoracic CT images taken for different indications between

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